Metabolic Peptide Journal

Evidence-based research on GLP-1 receptor agonists and metabolic peptides for weight management and metabolic health.

Metabolic Research

Semaglutide for Weight Loss: The Complete Clinical Guide

A comprehensive review of semaglutide's mechanism, titration protocol, clinical trial results, and what to expect from a physician-supervised weight management program.

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Metabolic Research

AOD-9604: The GH Fragment That Burns Fat Without the Side Effects

How AOD-9604 — a modified fragment of human growth hormone — stimulates lipolysis without causing insulin resistance or IGF-1 elevation.

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Metabolic Research

Tesamorelin: The Only FDA-Approved Peptide for Visceral Fat Reduction

How tesamorelin — the only FDA-approved peptide for visceral fat reduction — works, who it's indicated for, and what clinical trials show.

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Metabolic Research

MOTS-c: The Mitochondrial Peptide That Activates AMPK and Reverses Insulin Resistance

How MOTS-c — encoded in mitochondrial DNA — activates AMPK to improve insulin sensitivity and metabolic flexibility through mechanisms distinct from GLP-1.

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Metabolic Research

GH Secretagogues for Body Composition: Ipamorelin, CJC-1295, and GHRP-2 Compared

A comprehensive comparison of GH secretagogues for body composition — how they differ in selectivity, GH pulse amplitude, and metabolic effects.

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Metabolic Research

GLP-1 vs. AOD-9604: Two Different Approaches to Peptide-Based Weight Loss

How GLP-1 receptor agonists and AOD-9604 approach weight loss through fundamentally different mechanisms — and when to use each.

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Metabolic Research

NAD+ and Metabolic Rate: How NAD+ Decline Drives Metabolic Aging

How the age-related decline in NAD+ impairs mitochondrial function, reduces metabolic rate, and contributes to the weight gain associated with aging.

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Metabolic Research

Cagrilintide + Semaglutide (CagriSema): The Next Generation of Weight Loss Peptides

How combining the amylin analog cagrilintide with semaglutide produces additive weight loss beyond what either compound achieves alone.

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